'Living Doll' Composed of Collagen Cells.
To demonstrate a new method for fabricating three-dimensional living biological structures, researchers at the University of Tokyo’s Institute of Industrial Science (IIS) have created a 5-millimeter tall doll composed of living cells.
Researchers created the tiny figurine by cultivating 100,000 cell capsules of 0.1 millimeter balls of collagen, each coated with dozens of skin cells.
After the cell capsules had coalesced to form the doll-shaped mass of tissue, it was placed in a culture solution, where it reportedly survived for more than a day.
The researchers also successfully tested the biofabrication method with human liver cells. The technique can laso be used to create bodily organs and tissues with complex cellular structures, which may prove useful in the fields of regenerative medicine and development.
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