Friday, 8 January 2010

Mouse Teeth and the End of the Dentist as We Know It.

A mouse has grown a new tooth in place of a lost molar.

But hold on! We've all done that as a kin.

Well the news is it's a tooth that come via a new breakthrough in bioengineering. It has the same performance properties of the old tooth, and is strong and durable enough to allow the mouse to chew food normally over it's life.

To create the new tooth, the researchers @ Tokyo University of Science took 'Epithelial' cells and 'Mesenchymal' cells (about 50,000 each) from a mouse embryo and cultivated them together in a collagen-based medium to create a tiny tooth bud — a mass of tissue that has the potential to develop into a tooth.

They then implanted the 0.5-mm tooth bud into the jawbone of an mouse in place of a lost tooth. After 37 days, a new tooth sprouted, and after 50 days, it had grown to the same height as the adjacent teeth. The bioengineered tooth has the same hardness as ordinary teeth and it contains vessels and nerves, making it sensitive to external stimuli and pain.

This research is expected to advance the development of 'tooth regenerative therapy,' which one day will allow doctors to replace diseased or damaged teeth with bioengineered teeth grown from stem cells such as induced pluripotent stem (iPS) cells.

This type of treatment could not only ultimately eliminate the need for dentures and false teeth, but grow artificial teeth with new performance properties.

Imagine: once you have your new set, no more dentist, self-cleaning teeth, super-strong, and eventual teeth grown to your own design specification. Within a decade, start looking out for designer teeth shaped as Jewelry!!!

Goldie watch out. Click here and see!
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